Partners

OPTIMA
The Oxford Project to Investigate Memory and Ageing (OPTIMA) is an ongoing longitudinal multidisciplinary study. The 900 current subjects (control subjects and patients with dementia)have been followed for several years. Every
year each subject is examined by neurological and neuropsychological tests, CT and SPECT
brain scans, and biochemical analysis of blood and cerebrospinal fluid. After death the brain is examined by histochemical and biochemical methods.

OPTIMA provides the AD patients and controls for the clinical trials (completed and ongoing)that we fund. OPTIMA handles the sample acquisition and patient follow-up and sends patients’ blood samples to the Nagy laboratory at the University of Birmingham, which performs the analysis.